Hormone Support for Mood, Sleep, and Mental Health

Telehealth Integrative Psychiatry for Perimenopause and Menopause Symptoms

Hormonal shifts can affect far more than cycles and hot flashes. For many women, the transition through perimenopause and menopause brings changes in mood, anxiety, sleep, attention, motivation, and emotional resilience.

At LifeSync Health, we offer hormone-informed mental health care through telehealth in multiple states (Colorado, Minnesota, Wyoming, Montana, Oregon, Arizona, Nevada, Iowa, and Florida). When hormones are contributing to symptoms like depression, anxiety, irritability, insomnia, or brain fog, addressing hormonal balance can be an important part of a comprehensive mental health plan.

Because insurance billing rules differ based on the reason hormones are being used, we approach this clearly:

If we’re using hormone support primarily to improve mental health symptoms (mood, anxiety, sleep, cognition), visits may be eligible under mental health/psychiatric billing.
If the main goal is non-mental-health optimization (weight, libido, general wellness, aging, performance, etc.), we typically use a functional medicine appointment structure.

This helps keep care ethical, transparent, and aligned with payer requirements.

How Hormones Affect Mental Health

Sex hormones influence neurotransmitters and brain signaling systems involved in:

Mood stability
Anxiety regulation
Sleep quality and circadian rhythm
Attention, motivation, and executive functioning
Stress response and emotional regulation

During perimenopause, hormones can fluctuate dramatically before eventually declining after menopause. For many women, these shifts correlate with:

Increased anxiety or panic symptoms
Depressive symptoms or low motivation
Sleep disruption (difficulty falling or staying asleep)
Irritability or mood reactivity
“Brain fog,” reduced focus, or worsened ADHD symptoms
Depression
Anxiety
ADHD
Bipolar Disorder

Our Hormone Philosophy

LifeSync Health’s approach is practical and patient-centered:

Start with symptoms and goals. We focus on what you’re experiencing and how it’s impacting daily life.
Look for root contributors. Hormones may be part of the picture — but so can thyroid function, sleep debt, nutrient status, inflammation, stress physiology, and medication side effects.
Integrate treatment options. When appropriate, hormone support can be combined with psychiatric medication management, lifestyle strategy, and targeted supplementation.
Use careful monitoring. Any hormone plan should be monitored for response, tolerability, and safety.

The Menopause Method and Dr. Daved Rosensweet, MD

Dr. Daved Rosensweet is the founder/medical director of The Menopause Method and is associated with training clinicians in bioidentical hormone approaches.

The Menopause Method describes its program as “customized treatment programs” using “bio-identical hormones in an organic base.”

The Menopause Method site (program overview)
Dr. Rosensweet’s physician site (professional background)
YouTube interview/podcast episode (patient-friendly explanation)

Topical vs. Oral vs. Pellet Hormone Therapy

Hormone therapy can be delivered in several forms. Each has potential advantages and considerations.

Topical (Transdermal) Hormones

Topical hormones are applied to the skin and absorbed into the bloodstream. In the program we utilize, hormones are compounded and suspended in an organic oil base prepared by a compounding pharmacy.

Potential benefits of topical delivery include:

Avoiding first-pass liver metabolism
Steadier absorption in some individuals
Flexible dosing adjustments
Customization through compounding

The organic oil base is designed to enhance skin absorption and minimize exposure to synthetic fillers or chemical solvents.

Because these formulations are compounded, careful prescribing and monitoring are important to ensure appropriate dosing and response.

Oral Hormones

Oral hormones are taken by mouth and processed through the liver before entering systemic circulation.

Some individuals tolerate oral therapy well, but it may:

Affect clotting risk differently than transdermal routes
Influence liver metabolism
Have different effects on triglycerides and inflammatory markers

Route of administration is chosen based on individual risk factors, goals, and medical history.

Pellet Therapy

Pellet therapy involves implanting small hormone pellets under the skin that release hormone gradually over time.

While some individuals prefer this option for convenience, it offers less dosing flexibility once placed. Adjustments cannot be made until the pellet dissolves.

For patients whose primary goals involve mood stabilization and careful titration, a topical compounded approach may allow more precise symptom-guided adjustments.

Bioidentical vs. Synthetic Hormones

The term “bioidentical” refers to hormones that are chemically identical to those produced in the human body.

Compounded bioidentical hormone therapy is distinct from standardized, FDA-approved hormone formulations. National medical bodies emphasize the importance of understanding both the potential benefits and limitations of compounded therapies.

At LifeSync Health, decisions are based on:

Clinical symptoms
Risk assessment
Patient preference
Safety monitoring
Evidence-informed discussion

The goal is thoughtful, individualized care — not trend-based prescribing.

Brite and Topical Bioidentical Hormones in an Organic Oil Base

A distinguishing feature of the Brite model is its emphasis on the vehicle (the base) used for topical hormone delivery.

Brite states that patients apply a significant amount of topical base over time and emphasizes that its products use 100% certified organic oil bases and contain zero chemical solvents.

The Menopause Method similarly highlights “bio-identical hormones in an organic base,” aligning with the topical delivery concept.

What “compounded” means in this context

When hormones are compounded, the formulation is prepared by a compounding pharmacy based on a prescribed plan. Compounded bioidentical hormone therapy is a complex area with important considerations around quality, consistency, and evidence — and national bodies have published reviews discussing benefits, limitations, and safety considerations.

How we present this clinically:
We focus on using an individualized plan when appropriate, emphasizing:

careful dosing decisions
consistent follow-up
symptom-based outcomes
safety screening and monitoring

Can Hormones Help You?

This service is often a fit for individuals experiencing:

Perimenopause-related anxiety, irritability, or mood swings
Depression symptoms that worsen cyclically or hormonally
Sleep disruption that began or worsened with midlife hormone changes
Worsening ADHD symptoms, motivation, or “brain fog”
Postpartum or reproductive transition mood symptoms (case-by-case)

If binge eating, cravings, or weight changes are tightly linked to mood and stress physiology, you can also add an internal link to your:

Binge Eating & Weight Loss page

How Care Works

Initial evaluation
We review symptom history, psychiatric history, medications, sleep, stress load, and any prior hormone therapy experience.
Clarify the clinical goal
We document whether the hormone plan is aimed at mental health symptom relief (mood, anxiety, sleep, cognition) versus non-psychiatric optimization (which would be routed through a functional medicine structure).
Treatment plan
When appropriate, we may integrate:
- psychiatric medication optimization
- hormone-informed support (including topical bioidentical hormones in an organic oil base via compounding pharmacy, when clinically indicated)
- sleep and circadian strategy
- nutrition / metabolic support
- therapy tools and skills-based recommendations
Follow-up and monitoring
We track symptom change over time and adjust carefully.

Insurance and Appointment Types

To keep things clear:

Mental health billing may apply when hormone support is being used to target mental health symptoms (e.g., perimenopausal depression, anxiety, insomnia, irritability, cognitive changes).
Functional medicine appointments are used when the primary focus is non-psychiatric goals (e.g., general wellness optimization, weight loss as the central goal, libido as the central goal, anti-aging, etc.).

If you are unsure if you should book a mental health appointment or a functional medicine appointment, choose a complimentary Meet & Greet and we will work out the details together.

Book an Appointment

Additional Resources

The Menopause Method (program overview)
Brite (organic oil base philosophy)
National Academies report on compounded bioidentical hormone therapy (balanced discussion)
NCBI overview chapter on compounded bioidentical hormone therapy

Getting Started Is As Easy As 1..2..3..

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